Self-antigens may represent self-proteins that are denatured or otherwise modified after being produced on ribosomes, thus exposing novel epitopes
(immune-recognized domains, typically short peptide or carbohydrate sequences) which are then taken up and processed by antigen-presenting cells and made available to receptive T-cells.
A:自体抗原可以代表自体蛋白,自体蛋白在产生于核蛋白上之后被变性或修饰,因此暴露新的表位(免疫识别区域,通常是短肽或糖序列),后者被抗原呈递细胞占据和加工,并呈递给接受的T细胞。
B:自体抗原可以代表自体蛋白,自体蛋白在产生核蛋白之后被变性或修饰,因此暴露新的表位(免疫识别区域,通常是短肽或糖序列),后者被处理,被抗原表达的细胞加工,使适合于受体-T细胞。
个人更认同A版本。请高手指教!谢谢! |
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